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pLAPSN contains elements derived from Moloney murine leukemia virus (MoMuLV) and Moloney murine sarcoma virus (MoMuSV), and is a control vector for establishing a retroviral gene delivery and expression system. This vector was created by cloning the gene for human placenta alkaline phosphatase (AP) into the Xho I site in the multiple cloning site of the pLXSN Retroviral Vector. Upon transfection into a packaging cell line, pLAPSN can transiently express, or integrate and stably express. The 5’ viral LTR in this vector contains promoter/enhancer sequences that control expression of the alkaline phosphatase gene.

secreted alkaline phosphatase from human placenta

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